Calcifying odontogenic cyst (COC) is an uncommon odontogenic lesion that represents less than 2% of all odontogenic cysts and tumors. It usually occurs in incisor and canine areas during the second to fourth decades of life. It can be associated with other lesions like odontoma, Ameloblastic Fibroma, Ameloblastoma, Adenomatoid odontogenic tumors, Odontoameloblastoma, and Odontogenic Myxoma. Ameloblastic fibroma is a truly mixed tumor usually diagnosed within the posterior mandible during the first two decades of life. In the present article, a hybrid odontogenic tumor composed of COC and Ameloblastic Fibroma in a 14-year-old white Persian female is described.