Document Type: Original Article


1 Dept. of Oral Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

2 Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

3 Dept. of Nephrology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.


Statement of the Problem: Systemic conditions can affect the salivary glands and oral health. Hypertension induces xerostomia. Because the function of saliva is related to its quality and quantity, therefore, any changes in saliva can lead to diminished quality of patient’s life.
Purpose:  The purpose of this studywas to evaluate the relationship between hypertension and pH and viscosity of cumulative saliva in adults with hypertension.
Materials and Method: This cross sectional study took place on patients referred to oral medicine faculty of Shahid Sadoughi University of Medical Science. The patients’ blood pressure was measured and the 135 patients fitting the inclusion criteria participated in the study. Their unstimulated cumulative saliva was collected by spitting method and pH of the samples was measured by digital pH-meter set. Viscosity of the samples was measured by comparing the amount of saliva displacement in the thistle tube with control fluids at mm/10 seconds. The data was analyzed by Spss 20 software and ANOVA Tests and Tukey multiple comparison and their nonparametric equivalent (p≤ 0.005).
Results: This study showed that a significant relationship exists between pH and also viscosity of unstimulated saliva of normotensive and borderline hypertensive patients (pp< .005, respectively) and also between normotensive and stage I hypertensive patients (p<.0001, p<0.000). So, there is a direct and significant relationship between saliva viscosity and hypertensive patients and this relationship is reverse between saliva pH and hypertension.
Conclusion: Hypertension can cause an increase in viscosity and a decrease in pH of saliva in hypertensive patients that leads to salivary quantitative and qualitative changes and influences the oral health and quality of the patient’s life.