Document Type : Case Report

Authors

1 Dept. of Oral and Maxillofacial Pathology, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

2 Postgraduate Student, Dept. of Oral Pathology, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

3 Dept. of Oral and Maxillofacial, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

4 Dept. of Oral and Maxillofacial Surgery , School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

5 Postgraduate Student, Dept. of Endodontic, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Abstract

The granular cell odontogenic tumor is an extremely rare odontogenic neoplasm which about 38 cases has been reported with sufficient documentation in the literature. It has a prominent predilection to occur in the posterior of mandible of middle-aged women. Here, we report a case of mandibular granular cell odontogenic tumor in a 57-year-old female with chief complaint of swelling and tooth mobility. As rarity of these lesions, their clinical behavior and prognosis are not clear; hence, reporting more such cases may be beneficial to correct diagnosis and prevent unnecessary treatment.

Keywords

1. Sarode SC, Sarode GS, Vaidya K. Central granular cell odontogenic tumor: a systematic review. J Oral Pathol Med. 2014; 43: 167–176. [PubMed[Google Scholar]
2. Soluk-Tekkeşin M, Wright JM. The World Health Organization Classification of Odontogenic Lesions: A Summary of the Changes of the 2017 (4th) Edition. Turk Patoloji Derg. 2018; 34: 1–18. [PubMed[Google Scholar]
3. Meer S, Altini M, Coleman H, Daya N. Central granular cell odontogenic tumor: immunohistochemistry and ultrastructure. Am J Otolaryngol. 2004; 25: 73–78. [PubMed[Google Scholar]
4. Rinaggio J, Cleveland D, Koshy R, Gallante A, Mirani N. Peripheral granular cell odontogenic fibroma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007; 104: 676–679. [PubMed[Google Scholar]
5. Piattelli A, Rubini C, Goteri G, Fioroni M, Maiorano E. Central granular cell odontogenic tumour: report of the first malignant case and review of the literature. Oral Oncol. 2003; 39: 78–82. [PubMed[Google Scholar]
6. Yih WY, Thompson C, Meshul CK, Bartley MH. Central odontogenic granular cell tumor of the jaw: report of case and immunohistochemical and electron microscopic study. J Oral Maxillofac Surg. 1995; 53: 453–459. [PubMed[Google Scholar]
7. Gardner DG. Central odontogenic fibroma current concepts. J Oral Pathol Med. 1996; 25: 556–561. [PubMed[Google Scholar]
8. Cheng SJ, Wang YP, Chen HM, Chiang CP. Central granular cell odontogenic tumor of the mandible. J Formos Med Assoc. 2013; 112: 583–585. [PubMed[Google Scholar]
9. Silva BS, Yamamoto FP, Cruze Silva BT, Souza Aquime JR, Shinohara EH, Pinto Ddos S Jr. Central granular cell odontogenic tumor of the maxilla. J Craniofac Surg. 2012; 23: e117–e119. [PubMed[Google Scholar]
10. Ardekian L, Manor R, Gaspar R, Laufer D. Central granular cell odontogenic tumor: case report and review of literature. J Oral Maxillofac Surg. 1998; 56: 1343–1345. [PubMed[Google Scholar]
11. Mesquita AT, Santos CR, Gomez RS, Jorge J, León JE, de Almeida OP. Central granular cell odontogenic tumor: a histopathologic and immunohistochemical study. Ann Diagn Pathol. 2009; 13: 405–412. [PubMed[Google Scholar]
12. de Sousa SO, de Araújo NS, Melhado RM, de Araújo VC. Central odontogenic granular cell tumor: immunohistochemical study of two cases. J Oral Maxillofac Surg. 1998; 56: 787–791. [PubMed[Google Scholar]
13. Sarode SC, Vaidya K, Sarode GS. Central granular cell odontogenic tumor of mandible: a case report. J Oral Maxillofac Surg Med Pathol. 2013; 25:189–92. [Google Scholar]
14. Anbiaee N, Saghafi S, Mohammadzadeh Rezaei M. Central Granular Cell Odontogenic Tumor: Report of a Case with CBCT Features. J Dent (Tehran) 2014; 11: 365–370. [PMC free article] [PubMed[Google Scholar]
15. Brannon RB, Goode RK, Eversole LR, Carr RF. The central granular cell odontogenic tumor: report of 5 new cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002; 94: 614–621. [PubMed[Google Scholar]