Document Type : Original Articles

Authors

1 Oral and Dental Disease Research Center, Oral and Maxillofacial Medicine Department School of Dentistry,

2 School of Dentistry, Shiraz University of Medical Sciences,

3 PhD, Departments of Bacteriology and Virology, Jahrom Medical School, Jahrom University of Medical Sciences, Shiraz, Iran

4 Postgraduate, Dept. of Periodontics, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.

10.30476/dentjods.2021.85691.1145

Abstract

Statement of the problem: There are global efforts for introducing new herbal antimicrobial agent with minimal side effects. There are some reports about antimicrobial properties of pimpinella anisum and oregano vulgare.
Purpose: In this study the antimicrobial properties of pimpinella anisum and oregano vulgare have been assessed.
Material and Method: In this study, the dental plaque samples were collected from children aged 3-5 years old who were referred to a dental office with diagnosis of dental caries. After determination of the bacterial colonies of sanguinis and S.mutans and S.Salivaris, the minimum inhibitory concentration(MIC) and minimum bacteriocidal concentration (MBC) of ethanolic and methanolic extracts of Pimpinella anisum and Oregano vulgare were measured by macrodilusion and microdilusion method.
Result: The mean MIC and MBC of P.anisum extract and O.vulgare extract and their combination against S.mutans, S.sanguinis and S.salivarius were statistically different (P.value

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