Document Type: Original Article


Dept. of Oral and Maxillofacial Pathology, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.


Statement of problem: Orofacial tumors are a heterogeneous group of lesions having various histological types and clinical behavior. The prevalence and clinical behavior of some pathologic lesions is different in various populations.Purpose: The aim of this study was to determine the type and distribution of orofacial tumors among patients referred to the Oral Pathology Departments of Shiraz Dental School and Chamran Hospital in Iran.Materials and Method: In this retrospective case series study, data on the type, age, sex and site of tumors in 2343 patients with orofacial lesions in the period from 1991-2008 were collected and analyzed, using SPSS13.Results: In this study, 300 (12.8%) tumors were found among the subjects. The most common types of benign and malignant tumors were odontoma and langerhans cell histiocytosis in children and adolescents, and unicystic ameloblastoma and squamous cell carcinoma in the adults, respectively. The most common site of tumors in soft tissue was gingiva and in the jaws it was the posterior part of the mandible.Conclusion: The observed differences in the tumor type and distribution in this study compared with the previous studies, in addition to design and methods of the study, may be attributed to genetic and geographic variations in the population. Therefore, more extensive investigations are recommended to achieve more information about these lesions which can be used for assessment of patients.Key words: Prevalence, Orofacial tumors, Maxillofacial pathology