Langerhance Cell Histiocytosis with Primary Oral Manifestations; A case study

Ghalyani, P.; Sarrafan, N.; Pishva, S.

Langerhance Cell Histiocytosis with Primary Oral Manifestations; A case study

Document Type : Case Report

Authors

P. Ghalyani ¹

N. Sarrafan ²

S. Pishva ³

¹ Dept. of Oral Medicine, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran

² Dept.of Oral Medicine, School of Dentistry, Rafsanjan University of Medical Sciences, Rafsanjan, Iran

³ Periodontist

Abstract

Introduction: Histiocytosis of the langerhans cell is a rare disorder with unknown etiology and a spectrum of disorders characterized by proliferation of the histiocyte-like cells. It presents as Eosinophilic granuloma, Hand-schuller Christian disease, and Letter-siwe disease. The incidence rate is 2.1 in 200.000 child per year.Case Report: The patient was a 3.5 year old male child reffered with swelling of the gingival and hypermobility of the deciduous molar teeth.The diagnostic procedures until the final diagnosis of langerhance cell histiocytosis and treatment of this case are reported.Conclusion: Oral lesions could be the first manifestion of histiocytosis of the langerhans cell, of which the dentists should be aware. The early diagnosis is so important in treatment and survival of the patient.Key words: Langerhance cell, Histiocytosis, alveolar bone, Hypermobility of teeth