Journal of Dentistry

The Effect of Citalopram and Colonazpam on Burning Mouth Syndrome

Document Type : Original Article

Authors

H. Ebrahimi 1
S. Pourshahidi 1
A. Andisheh Tadbir 2

1 Dept. of Oral Medicine, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.

2 Dept. of Oral Pathology, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.

https://doi.org/10.30476/dentjods.2019.43615
Abstract
Statement of problem: Psychosocial factors are thought to play a role in burning mouth syndrome (BMS) and several therapeutic approaches for BMS are based on this consideration.Purpose: This paper evaluated the efficacy of the combined systemic administration of citalopram and clonazepam, as anti-depressant and anti-anxiety drugs, in the management of burning mouth syndrome and reduction of the burning sensation.Materials and Method: In this cross-sectional study, 80 subjects suffering from idiopathic burning mouth syndrome were enrolled. The patients underwent a thorough clinical examination. Oral symptoms before and after treatment were assessed using a Visual Analogue Scale. The mean duration of burning in our patients was 7 months. Systemic combination of citalopram (20 mg/daily) and clonazpam (0.25 mg/daily) was prescribed for all of them for 8 weeks. Then, the data were analysed, using Student’s t-test.Results: Of the 62 patients who completed the protocol, 38 reported complete remission of the oral burning sensation. However, 20 patients reported a little improvement, and four of them reported no improvement.Conclusion: These data suggest that citaloperam with colonazpam is effective in patients with BMS
Journal of Dentistry
Volume 9, Supplement 2008
34
Autumn 2008
Pages 31-34

  • Receive Date 22 October 2013
  • Accept Date 05 February 2019
  • First Publish Date 05 February 2019
  • Publish Date 01 October 2008

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