Document Type : Original Article

Authors

1 Dept. of Oral and Maxillofacial Pathology, Faculty of Dentistry, Kurdistan University of Medical Sciences, Sanandaj, Iran.

2 Dept. of Medical Virology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.

10.30476/dentjods.2021.88551.1338

Abstract

Statement of the Problem: Oral health status has been suggested as one of the possible risk factors for oral human papillomavirus (OHPV) infection. Anyway there is inconsistent evidence regarding its relationship to the presence of OHPV.
Purpose: This study aimed to compare oral health status between two groups of patients with and without OHPV infection.
Materials and Method: This cross-sectional study was performed on 272 oral rinse samples, collected from our previous study population. After signing the form of written informed consent an oral examination to determine some clinical parameters of oral health status [including: periodontal disease status, oral hygiene status, decayed, missing, and filled teeth (DMFT) of participants] was conducted. Next, viral deoxyribonucleic acid (DNA) extraction, polymerase chain reaction (PCR), and HPV genotyping were performed on the samples.
Results: OHPV DNA was detected in a total 31 (11.40%) samples that were considered as OHPV+ group. None ofthe determined clinical parameters of oral health status were significantly different between OHPV+ and OHPV DNA negative (OHPV-) groups (p> 0.05).
Conclusion: Asthe findings did not indicate a significant association between oral health status and OHPV further studies with larger sample size are recommended to reach a definite conclusion about the association of them.

Keywords