Pacinian Neurofibroma of Oral Cavity: A Rare Neurogenic Tumor

Amanpour, Sara; Malekpour Afshar, Reza; Parastar, Alireza

doi:10.30476/dentjods.2025.104390.2527

Pacinian Neurofibroma of Oral Cavity: A Rare Neurogenic Tumor

Document Type : Case Report

Authors

Sara Amanpour ¹

Reza Malekpour Afshar ²

Alireza Parastar ³

¹ Dept. of Oral and Maxillofacial Pathology, Faculty of Dentistry, Kerman University of Medical Sciences, Kerman, Iran.

² Pathology and Stem Cell Research Center, Kerman University of Medical Sciences, Kerman, Iran.

³ Resident of Oral and Maxillofacial Surgery, Faculty of Dentistry, Kerman University of Medical Sciences, Kerman, Iran.

https://doi.org/10.30476/dentjods.2025.104390.2527

Abstract

Pacinian neurofibroma is a rare variant of neurofibroma composed of structures resembling pacinian corpuscles at various stages of maturation. It is a rare neurogenic tumor which has been reported predominantly on hands, and feet, where pressure receptors are typically located. It usually presents as a solitary nodule and is not reported in associated with von Recklinghausen’s disease or any other syndrome. The intraoral site is unusual. The purpose of this report is to present a rare case of intra-oral pacinian neurofibroma associated with neurofibromatosis type 1 and to describe its clinical and microscopic features contributing for the best knowledge about this rare entity.

Highlights

Sara Amanpour (Google Scholar)

Keywords

Neurofibroma

Pacinian Corpuscles

Oral cavity

Case report

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