Document Type : Case Reports

Authors

1 Dept. of Oral Medicine and Radiology, Kalinga Institute of Dental Sciences, Bhubaneswar, Odisha, India.

2 Dept. of Dentistry, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.

10.30476/dentjods.2026.109909.2921

Abstract

The swelling that affects the face, lips, and tongue is known as angioedema. It is typically localized, asymmetrical, and mildly uncomfortable. The deep dermis and subcutaneous cellular tissue are affected by increased vascular permeability brought on by various bio-chemical mediators produced by mast cells (histamine, leukotrienes, prostaglandins), bradykinin, and complement products. This can cause swelling on the back of the hands, feet, and genitalia. Activation of the kallikrein-kinin cascade or mast cell degranulation can both result in angioedema. Acute urticaria or a more widespread anaphylactic reaction can also result from immunoglobulin E (IgE)-mediated hypersensitivity to foods or medications, which can also produce angioedema in the former scenario. This case report aims to present the clinical features and treatment of the angioedema in a 49-year-old male complaining of pain and swelling in the lower lip region.

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