Journal of Dentistry

Congenital Leiomyomatous Hamartoma of the Anterior Maxillary Gingiva with 4-Year Follow-up: A Rare Case Report and Literature Review

Articles in Press

Document Type : Case Report

Authors

Hanieh Jadidi 1
Sara Tavassoli-Hojjati 1
Fatemeh Shahsavari 2
Maedeh Ghorbanpour 2
Mahnegar Shariati 3

1 Dept. of Pediatric Dentistry, School of Dentistry, Tehran Medical Sciences, Islamic Azad University of Medical Sciences, Tehran, Iran.

2 Dept. of Oral and Maxillofacial Pathology, Tehran Medical Sciences, Islamic Azad University of Medical Sciences, Tehran, Iran.

3 ept. of Pediatric Dentistry, School of Dentistry, Iran University of Medical Sciences, Tehran, Iran.

10.30476/dentjods.2026.109963.2925
Abstract
This report presents a rare case of congenital oral leiomyomatous hamartoma (OLH) involving the anterior maxillary gingiva and includes a review of previously reported cases and the present case. A 5.5-year-old girl presented with a solitary, painless, and exophytic lesion on the labial gingiva that had been present since birth and had gradually increased in size. Based on the clinical presentation, the lesion was provisionally diagnosed as congenital epulis. However, histopathological examination revealed features consistent with OLH. The patient underwent excisional biopsy and was followed for 4 years, during which no recurrence was observed. The presence of a polypoid lesion in the midline region of the anterior maxillary gingiva should prompt consideration of OLH in the differential diagnosis. Comprehensive histopathological evaluation, supplemented by immunohistochemical staining when indicated, is essential for establishing an accurate diagnosis and guiding appropriate management. This case contributes to the limited literature on OLH by providing additional insights into its clinical presentation, diagnosis, treatment, and favorable prognosis, while emphasizing the importance of meticulous histopathological evaluation.

Keywords

Hamartoma
Leiomyoma
Congenital Abnormalities
Gingiva
Mouth Neoplasms
Journal of Dentistry

Articles in Press, Accepted Manuscript
Available Online from 21 October 2026

  • Receive Date 10 December 2025
  • Revise Date 26 September 2026
  • Accept Date 17 October 2026
  • First Publish Date 21 October 2026
  • Publish Date 21 October 2026

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